IBUMOL®
IBUMOL®-400 Paracetamol and Ibuprofen Tablets Composition: Each uncoated tablet contains: Paracetamol BP............325 mg Ibuprofen BP.................400 mg DESCRIPTION Ibumol is an anti-inflammatory analgesic combination. Ibuprofen is a potent anti-inflammatory with analgesic and antipyretic action. Its analgesic and antipyretic effects are further reinforced by Paracetamol. CLINICAL PHARMACOLOGY Mechanism of action: Ibuprofen is a non steroidal anti-inflammatory agent used in painful inflammatory conditions. This acts by biosynthesis and release of prostaglandins in the cells. It inhibits the enzymes prostaglandin synthetase. Paracetamol is an analgesic and antipyretic agent. It is a weak anti-inflammatory agent as it is a weak inhibitor of cyclo-oxygenase in presence of high concentrations of peroxides that are found in inflammatory lesions. Paracetamol does not inhibit neutrophil activation as other NSAIDs. The antipyretic activity is due to the direct acti...